Akali excels at killing weaker characters. Let your team initiate and then strike at the people in the back.
Find the balance between storing Essence of Shadows, and using Shadow Dance before having max charges.
Akali can still be hit by area effect spells while invisible inside Twilight Shroud.
Akali greatly benefits from both Mejai's Soulstealer and the Sword of the Occult. Watch which items she gets and prioritize her accordingly.
Return to base if your Health is low and Akali has multiple charges of her ultimate.